The cuts will impact multiple teams including marketing departments for its film and television units.
Workers in Disney's casting and development and corporate finance departments will also be affected.
"We have been surgical in our approach to minimise the number of impacted employees," said a spokesperson. The company also said that no teams will be closed down entirely.
The California-based firm employs 233,000 workers, with just over 60,000 of those based outside the US.
Disney owns a host of companies across the entertainment industry including Marvel, Hulu and ESPN.
The firm reported stronger than expected earnings in May, with overall revenue of $23.6bn for the first three months of the year. That was a 7% increase from the same period in 2024.
It said the growth was fuelled by new subscribers to its Disney+ streaming service.
The company has released a number of new films this year including Captain America: Brave New World and Snow White.
The live action remake of the iconic Snow White animated film did not perform as well as expected at cinemas, after facing a number of negative reviews.
But Disney's latest release, Lilo & Stitch, broke box office records in the US for the Memorial Day holiday weekend.
The animated film has seen global ticket sales of more than $610m since its release in May, according to industry data firm Box Office Mojo.