Radio 1 Breakfast host Greg James says Sam Fender's main stage headline slot on Saturday will be "incredibly significant".
"He's an artist that Radio 1 has supported from day one," says Greg.
"We all knew that something special could happen with him, and it has."
Official UK Chart Show host Jack says the weekend is a chance for him to watch artists he's interviewed performing.
"Joy Crookes is an artist who I've never seen live before who I love to hang out with on the radio," he says.
"She's so much fun. Her music is so soulful, so euphoric and she is just a great time and I think her set's going to be a great time."