To date, there have been no human cases of West Nile virus acquired in the UK - although, since 2000, there have been seven cases of the disease linked to travel to other countries.
West Nile virus is usually present in several regions across the world, including parts of Africa, Asia, South America and Europe, and has expanded in recent years.
Research by the UKHSA and the Animal and Plant Health Agency (APHA) found fragments of the virus in mosquitoes collected at ponds near Retford, Nottinghamshire in 2023.
"While this is the first detection of West Nile Virus in mosquitoes in the UK so far, it is not unexpected as the virus is already widespread in Europe," said Dr Meera Chand, a deputy director for travel health and infections at UKHSA.
Dr Arran Folly, who led the project which found the virus, said its detection is part of a "wider changing landscape, where, in the wake of climate change mosquito-borne diseases are expanding to new areas".
While the Aedes vexans mosquito is native to Britain, he added that warming temperatures may bring non-native species to the UK and, with them, the potential of infectious disease.
West Nile virus causes either very minor symptoms or none at all - but around 20% of infected people can experience headaches, high fever and skin issues. In rare cases, it can kill through serious brain illnesses, including encephalitis or meningitis.
No specific treatment or vaccines exist for humans.