Staff at the University of Edinburgh are being balloted on strike action in a dispute over plans to cut £140m from its budget.
The Universities and Colleges Union (UCU) claimed the university had refused to rule out compulsory redundancies as part of the cuts.
The union said there was "no need" for the institution to make that level of cuts, describing it as a "manufactured crisis".
It comes after the university's principal, Prof Peter Mathieson, suggested free tuition for Scottish students was not sustainable due to the financial strains on higher education.