It will offer a range of indoor and outdoor activities including an indoor water park.
Chief executive Colin McKinlay said: "This is a tremendously exciting project and offers the opportunity to transform leisure and tourism in the Scottish Borders.
"Center Parcs is an exceptionally popular destination for families in the UK and Ireland and there is robust demand to support a seventh village.
"Throughout our history, we have demonstrated that a Center Parcs village provides significant economic benefits locally, regionally and nationally."
He said many Scottish families already visited their sites in England and this would bring the offering "closer to home".
The site is on land to the east of the A7 between Hawick and Selkirk which is owned by the Buccleuch Group.
Its executive chairman Benny Higgins said the project promised an "outstandingly positive impact" on tourism and leisure in the Scottish Borders.