The US said it had agreed to cut the tariffs it charges on goods from Taiwan to 15%, in exchange for hundreds of billions of dollars in investment aimed at boosting domestic production of semiconductors.
The Commerce Department said the island's semiconductor and technology enterprises had committed to "new, direct investments" worth at least $250bn (£187bn).
The deal also provides carve-outs from tariffs for Taiwanese semiconductor companies investing in the US.
Boosting US production of semiconductor chips, which are found in machines ranging from cars to smart phones, has been a priority for the US since shortages during the Covid-19 pandemic exposed supply chain risks.
