On Thursday night, Alaa Abdel Fattah and his mother were given the 2025 Magnitsky Award for "Courage Under Fire". Sanaa had to collect the award on their behalf.
Mr Abdel Fattah rose to prominence during the 2011 uprising in Egypt that forced long-time President Hosni Mubarak to resign.
He spent most of his time in prison after 2014, the year after Sisi led the military's overthrow of Egypt's first democratically elected president, Muslim Brotherhood leader Mohammed Morsi, following anti-government protests.
While in power, Sisi has overseen what human rights groups say is an unprecedented crackdown on dissent that has led to the detention of thousands of people.
In 2015, a court sentenced Mr Abdel Fattah to five years in prison for participating in an unauthorised protest.
In September 2019, only six months after he had been released on probation, he was arrested again and held in pre-trial detention for more than two years.
He was convicted in December 2021 of "spreading false news" for sharing a post about a prisoner dying of torture and handed another five-year sentence following a trial that human rights groups said was grossly unfair.
His 68-year-old mother, Leila, launched a 287-day hunger strike last September 2024 to protest against his imprisonment. She lost more than 40% of her original body weight and was twice admitted to hospital in London.