"I was both surprised and excited to be asked back to tread the streets of Walford once again and to be involved in Nigel's touching dementia storyline," St Clement, 83, said.
"It was lovely to be welcomed back by those with whom I had worked for so long. It was just like coming home."
Pat returns to help Nigel when his dementia symptoms intensify, following an emotional evening at his festive film screening.
St Clement first appeared in EastEnders in 1986 and was at the heart of the drama in Albert Square until her character's death.