The Israel Defense Forces (IDF) said that troops went to the scene "to disperse the confrontation using riot dispersal means and apprehended several Israeli civilians". It added that soldiers were then attacked by settlers gathering nearby and their vehicle was damaged.
Israeli police stated that four suspects were arrested.
In a post on X, Israeli President Isaac Herzog called the latest events "shocking and serious", blaming "a handful of violent and dangerous individuals".
He went on: "Such violence against civilians and against IDF soldiers crosses a red line and I condemn it severely."
The head of the IDF Central Command, Major-General Avi Bluth, also condemned the attacks, saying that such incidents "undermine the stability of the security situation".
"The reality in which anarchist fringe youth act violently against innocent civilians and against security forces is unacceptable and is extremely serious. It must be dealt with firmly," he told officers, in comments sent by the Israeli military.
"The directive to IDF soldiers is clear: do not stand idly by and do everything in your power to prevent any act of nationalist crime."
The large-scale attack on Tuesday was a rare instance of Israeli law enforcement acting to counter settler violence, which has increased dramatically since the Hamas-led attacks on Israel on 7 October 2023 triggered the Gaza war.
Israeli rights group Yesh Din said that of 1,701 police investigations into offenses committed by Israelis against Palestinians in the West Bank (not including East Jerusalem) between 2005 and 2024, 93.8% of concluded cases closed with no indictment filed.