Colbert told viewers The Late Show's cancellation was ultimately a financial decision - which is certainly a credible explanation.
Television is expensive to make, with huge teams of producers, directors, camera operators and other technical staff, not to mention the large fee for the presenter.
And while YouTubers can now offer an increasingly professional operation themselves, they can do so at a fraction of the cost.
But the cancellation still puzzled some. The Late Show was one of CBS's top shows, attracting an average audience of 2.57m viewers in 2024.
Its ratings actually improved under Colbert, particularly after it began skewering the Trump administration - the host is one of the president's most vocal critics.
As a result, some have questioned whether the show's cancellation has anything to do with political pressure.
Its closure comes after CBS parent company Paramount settled with US President Donald Trump over the editing of a 60 Minutes interview with Kamala Harris.
President Trump said the way his presidential rival's answer to a question about Israel was presented on two different platforms made her look more favourable to viewers.
CBS noted at the time its settlement did not include a statement of apology or regret. Business commentators said the deal was made partly so as to not affect Paramount's planned merger with Skydance Media, which Trump had the power to halt.
Speaking after the The Late Show's cancellation was announced, Democratic Senator Adam Schiff said: "If Paramount and CBS ended the Late Show for political reasons, the public deserves to know. And deserves better."
The sentiment was echoed by Democratic Senator Elizabeth Warren, who noted the show's cancellation came three days after Colbert's criticism of the Paramount settlement.
Their comments highlight the political climate in which this decision has been made, but CBS denied this was a factor.
In its statement, the network said it was a "purely financial decision" and "not related in any way to the show's performance, content or other matters happening at Paramount".