A player who has perhaps one of the biggest chances to impress is Aston Villa forward Morgan Rogers.
The 22-year-old has scored three goals and provided two assists in 11 games for his club side and the calls from outside the set-up for him to be included have probably been some of the loudest in recent weeks.
Rogers says he is ready to step up before the "clean slate" when Tuchel takes over.
"I just try and push myself everyday and see what new levels I can reach. I have probably surprised myself a bit at times this season in how well I have done," Rogers said.
"I have always believed in myself that I can get to this level and maintain it."
Rogers plays in an area of the pitch where England have a lot of depth - but with Foden, Palmer, Grealish and Saka all out, the forward could have a great chance to show what he can do in a hostile environment against opponents that took England apart in September.