People in clinically at-risk groups are being urged to get their free Covid-19 and flu vaccinations this winter.
NHS Cambridgeshire and Peterborough said only 27% of those eligible for the Covid vaccine, and 35% of those eligible for a flu vaccine in the two areas - plus Royston, in Hertfordshire - had come forward.
More than 68,000 people had yet to have their Covid vaccination and more than 74,000 people had not taken up the offer of protection against flu.
Cali Makewell, vaccination lead for the local service said: "It's very important to get these vaccines as you are at an increased risk of getting seriously ill without their protection."